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Sensitive determination of baicalein based on functionalized graphene loaded RuO2 nanoparticles modified glassy
Jiantong Qiao1, Yulong Zhang1, Sheng Lei1
1College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
Abstract:
The nanocomposite of ruthenium oxide (RuO2) loaded on Poly-(dimethyldiallylammonium chloride) (PDDA) functionalized reduced graphene oxide (RuO2-PDDA-rGO) was synthesized based on a one-step method. Based on the RuO2-PDDA-rGO modified glassy carbon electrode (GCE), a new electrochemical sensor (RuO2-PDDA-rGO/GCE) was fabricated and used in detection of baicalein for the first time. Compared with other reported electrochemical sensors for the detection of baicalein, the prepared RuO2-PDDA-rGO/GCE had a wider linear range (2-400 nM) and lower detection limit (0.6 nM, S/N = 3). The other advantages were the excellent repeatability of proposed method and good stability of prepared sensor.
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