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BET 2: Antiemetic use in paediatric sedation with ketamine

Lisa Dunlop1, Dani Hall1

  • 1Evelina London, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Emergency Medicine Journal : EMJ
|July 22, 2018
PubMed

Insights

Administering anti-emetics before procedural sedation in children may reduce the risk of vomiting. This review of studies suggests a benefit for using anti-emetic medications to prevent nausea and vomiting during medical procedures.

Area of Science:

  • Pediatric Anesthesiology
  • Pharmacology
  • Clinical Medicine

Background:

  • Procedural sedation in children is common.
  • Vomiting is a frequent side effect of procedural sedation.
  • Preventing vomiting is important for patient safety and procedure success.

Purpose of the Study:

  • To review the evidence on anti-emetic use during pediatric procedural sedation.
  • To determine if anti-emetics reduce vomiting incidence in sedated children.

Main Methods:

  • A literature search was conducted for relevant studies.
  • Included studies were reviewed and data tabulated.
  • Focused on randomized controlled trials and cohort studies.

Main Results:

  • Three randomized controlled trials and one cohort study were identified.
  • Findings suggest a reduced risk of vomiting with anti-emetic administration.
  • Evidence indicates a potential benefit of anti-emetics in this context.

Conclusions:

  • Anti-emetic administration appears to be associated with decreased vomiting during pediatric procedural sedation.
  • Further research may solidify these findings.
  • This supports the consideration of anti-emetics for preventing vomiting in sedated children.

Keywords:
emergency care systems

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