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Updated: Feb 7, 2026
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Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
Published on: May 5, 2011
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Detecting and quantifying activity/inflammation in localized scleroderma with thermal imaging.
I Ranosz-Janicka1, A Lis-Święty1, A Skrzypek-Salamon1
1Chair and Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
Summary
Infrared thermography (IRT) shows promise for objectively assessing localized scleroderma (LoS) activity. This method correlates well with clinical scores, aiding in the evaluation of skin inflammation and erythema in LoS patients.
Area of Science:
- Dermatology
- Medical Imaging
- Biophysics
Background:
- Localized scleroderma (LoS) disease activity is typically assessed using the LoS cutaneous assessment tool (LoSCAT).
- A need exists for more objective methods to evaluate LoS activity and inflammation.
- Infrared thermography (IRT) offers a potential objective measurement tool.
Purpose of the Study:
- To evaluate the correlation between LoS lesion severity, as scored by LoSCAT, and hyperthermia detected by IRT.
- To determine the utility of IRT in objectively quantifying inflammation in LoS.
Main Methods:
- LoS lesions were assessed independently using LoSCAT and IRT by two examiners.
- Average temperature (Tavg) of lesional dermis was measured and compared to contralateral healthy skin, calculating the temperature difference (ΔTavg).
- Measurements focused on areas with highest scores for erythema (ER), skin thickness (ST), dermal atrophy (DAT), and subcutaneous atrophy (SAT).
Main Results:
- One hundred and four LoS lesions in 40 adults were analyzed.
- IRT demonstrated 80.7% sensitivity and 86.3% specificity for detecting activity/inflammation.
- A significant positive correlation was observed between ΔTavg and clinical ER and DAT scores.
Conclusions:
- IRT may serve as a valuable tool for assessing erythematous LoS lesions and quantifying disease activity.
- IRT can aid in objectively evaluating inflammation, with clinical context helping to interpret potential false positives due to atrophy.
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