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Updated: Feb 7, 2026

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest
Published on: August 6, 2015
Three-vessel myocardial bridging: A possible cause of myocardial stunning
Ana Rita Almeida1, Ana Rita Pereira1, Gonçalo Morgado1
1Cardiology Department, Hospital Garcia de Orta, Almada, Portugal.
Insights
This case study highlights myocardial bridging affecting all three major coronary arteries, causing severe biventricular dysfunction. Effective medical therapy successfully restored heart function and improved patient outcomes.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Clinical Case Reports
Background:
- Myocardial bridging is a congenital anomaly where a segment of a coronary artery travels through the heart muscle.
- While common, bridging of all three major coronary arteries is exceptionally rare.
Observation:
- A rare case of myocardial bridging involving the left main, left anterior descending, and right coronary arteries is presented.
- The patient exhibited severe biventricular dysfunction and tachycardia, an unusual presentation.
Findings:
- Non-invasive multimodality cardiac imaging, including cardiac magnetic resonance (CMR), computed tomography angiography (CTA), and myocardial perfusion scintigraphy (MPS), was crucial for diagnosis.
- These imaging modalities enabled detailed visualization of the myocardial bridges and assessment of their functional impact.
Implications:
- This case underscores the importance of considering rare coronary anomalies in unexplained biventricular dysfunction.
- Successful management with targeted medical and neurohormonal therapy demonstrates a viable treatment approach for such complex cases.
- The findings contribute to understanding the clinical spectrum and diagnostic strategies for extensive myocardial bridging.
Abstract:
The authors report a rare clinical case of myocardial bridging of the three major coronary arteries, which manifested in an unusual way with severe biventricular dysfunction in the context of tachycardia. For the diagnosis, the authors relied on non-invasive multimodality cardiac imaging, including cardiac magnetic resonance, computed tomography angiography and myocardial perfusion scintigraphy. The implementation of targeted medical and neurohormonal therapy resulted in the recovery of ventricular function and clinical improvement.
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