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Gestational Gigantomastia Complicated by PTHrP-Mediated Hypercalcemia

Taher Modarressi1, Michael A Levine2,3, Julia Tchou4,5

  • 1Department of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

The Journal of Clinical Endocrinology and Metabolism
|July 23, 2018
PubMed
Summary

Gestational gigantomastia can cause hypercalcemia due to elevated parathyroid hormone-related protein (PTHrP). Termination of pregnancy rapidly resolved hypercalcemia, indicating the placenta as the PTHrP source.

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