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[Present status of the treatment for olfactory dysfunction]
1Department of Otorhinolaryngology, China-Japan Friendship Hospital, Beijing 100029, China.
Summary
Olfactory dysfunction, or loss of smell, can be treated with medications like glucocorticoids, endoscopic sinus surgery for sinusitis, and olfactory training. These methods show promise for improving smell perception across various causes.
Area of Science:
- Otolaryngology
- Neurology
- Pharmacology
Background:
- Olfactory dysfunction involves a decrease or loss of smell perception.
- It impacts quality of life and can stem from various underlying causes.
Purpose of the Study:
- To systematically review the classification, etiology, and diagnosis of olfactory dysfunction.
- To focus on advancements in the management of olfactory dysfunction.
Main Methods:
- Systematic literature review.
- Analysis of current therapeutic strategies including pharmaceutical, surgical, and olfactory training interventions.
Main Results:
- Glucocorticoids are crucial in treating olfactory dysfunction.
- Promising pharmaceutical agents include sodium citrate, vitamin A, and phosphodiesterase inhibitors.
- Endoscopic paranasal sinus surgery offers partial improvement for chronic sinusitis-related olfactory dysfunction.
- Olfactory training demonstrates efficacy across diverse etiologies of smell loss.
Conclusions:
- Current management strategies offer diverse options for olfactory dysfunction.
- Pharmaceuticals, surgery, and olfactory training represent key advancements in restoring smell perception.
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