[Application of multi-functional modularized prosthesis in reconstruction for sternal defect]

Objective: To investigate the feasibility and effectiveness of sternal reconstruction using a multi-functional modularized sternal reconstruction system. Methods: In June 2016 and August 2017, the modularized sternal prosthesis system was used on two patients for sternal reconstruction in the Department of Thoracic Surgery of Shanghai Pulmonary Hospital, Tongji University. Both patients were female aging 48 and 72 years, respectively, with the primary diagnosis of tumor of the lower sternal body and huge mediastinal tumor. Partial sternal resection and reconstruction was performed through median sternotomy. The multi-functional modularized sternal reconstruction system consisted of manubium, superior sternal body, inferior sternal body, rib and clavicle modules. Each module was designed into 3 to 6 sizes. Appropriate modules were chosen in each case to be assembled as a sternal reconstruction prosthesis. Results: Both operation were smooth, with operation time of 240 minutes and 280 minutes, intraoperative blood loss of 100 ml and 400 ml. The patients were followed up for 18 months and 4 months, respectively. In both cases, the sternal reconstruction was satisfactorily healed, without local infection, fluid accumulation, loose part or dislocation. No local recurrence or distant metastasis was found. Conclusion: The multi-functional modularized sternal reconstruction system can be safely and effectively applied for sternal reconstruction in 2 cases.