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Published on: May 20, 2018
Visual preconditioning reduces emergence delirium in children undergoing ophthalmic surgery: a randomised controlled
1Department of Anaesthesiology, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China.
Insights
Visual preconditioning with an eyepatch significantly reduces emergence delirium in children undergoing eye surgery. This simple intervention lowers the incidence and severity of delirium, though it may slightly increase recovery time.
Area of Science:
- Pediatric Anesthesiology
- Ophthalmology
- Child Psychology
Background:
- Emergence delirium is a frequent complication in pediatric ophthalmic surgery.
- Preschool-aged children are particularly susceptible to this post-anesthetic complication.
- Visual disturbance is a suspected contributing factor.
Purpose of the Study:
- To evaluate the efficacy of visual preconditioning in preventing emergence delirium.
- To assess the impact of prophylactic eyepatch use on post-operative delirium.
- To investigate the effect on emergence and recovery times.
Main Methods:
- A prospective, blinded, randomized study involving 179 children (3-7 years) undergoing unilateral cataract surgery.
- Participants were randomized into two groups: visual preconditioning (eyepatch) or programmed explanation.
- Emergence delirium was assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale.
Main Results:
- The visual preconditioning group showed a significantly lower incidence of emergence delirium (16.9% vs. 44.4%).
- Maximal PAED scores were significantly lower in the preconditioning group.
- Visual preconditioning was associated with prolonged emergence time and post-anesthesia care unit (PACU) stay.
Conclusions:
- Visual disturbance plays a role in emergence delirium for children undergoing ophthalmic surgery.
- Prophylactic eyepatch treatment is an effective strategy to reduce emergence delirium in this population.
- While effective, the intervention requires consideration of potential impacts on recovery duration.
Background:
Emergence delirium is a common complication in children, especially in preschool children undergoing ophthalmic surgery. The aim of the study was to investigate the effects of visual preconditioning (application of an eyepatch over the eye to be operated for ≥3 h the day before surgery) on emergence delirium after ophthalmic surgery under sevoflurane anaesthesia.
Methods:
One hundred and seventy-nine children undergoing unilateral cataract surgery, aged 3-7 yr, were involved in this prospective, blinded, randomised study. Subjects were randomised to receive visual preconditioning (Group P, n=89) or to receive programmed explanation the day before surgery (Group C, n=90). The primary outcome was incidence of emergence delirium evaluated by the paediatric anaesthesia emergence delirium (PAED) scale. The secondary outcomes included emergence time and post-anaesthesia care unit (PACU) stay time.
Results:
Children in Group P had a significantly lower incidence of emergence delirium than those in Group C [16.9% vs 44.4%, odds ratio (OR) 4.0, 95% confidence interval (CI) 2.0 to 8.0]. The maximal PAED score was lower in Group P than in Group C [4 (0-20) vs 9 (0-20), median difference -3.0, 95% CI -5.0 to -1.0]. Visual preconditioning prolonged emergence time (P<0.001) and PACU stay time (P=0.002).
Conclusion:
Visual disturbance contributes to emergence delirium in preschool children undergoing ophthalmic surgery with sevoflurane, and prophylactic eyepatch treatment can reduce emergence delirium.
Clinical Trials Registration:
NCT02590744.
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