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Updated: Feb 7, 2026

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
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Decrease in Intercourse Satisfaction in Men Who Recover Erections After Radical Prostatectomy.

Jean E Terrier1, Melissa Masterson2, John P Mulhall1

  • 1Male Sexual and Reproductive Medicine Program, Urology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

The Journal of Sexual Medicine
|July 24, 2018
PubMed
Summary
This summary is machine-generated.

Erectile function recovery after radical prostatectomy (RP) does not guarantee restoration of pre-surgery sexual satisfaction. Men experienced decreased intercourse satisfaction despite regaining erectile function, highlighting the need for comprehensive patient support.

Keywords:
Erectile DysfunctionErectile FunctionIntercourse SatisfactionInternational Index of Erectile FunctionProstate CancerProstatectomy

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Area of Science:

  • Urology
  • Sexual Medicine
  • Oncology

Background:

  • Radical prostatectomy (RP) is a common treatment for prostate cancer.
  • Erectile function recovery is often assumed to restore sexual satisfaction post-RP.
  • The relationship between sexual function and satisfaction after RP requires further investigation.

Purpose of the Study:

  • To determine if recovery of erectile function after radical prostatectomy restores presurgical levels of sexual satisfaction.
  • To analyze the impact of erectile function recovery on intercourse satisfaction post-RP.

Main Methods:

  • Prospective study of 229 men pre- and 24-months post-RP.
  • Assessment using the International Index of Erectile Function (IIEF) domains for erectile function (EFD) and intercourse satisfaction (ISD).
  • Erectile function recovery defined by EFD scores (≥24 or back to baseline [BTB]).

Main Results:

  • Significant decrease in both EFD and ISD scores from baseline to 24 months post-RP.
  • Intercourse satisfaction (ISD) declined even in men who recovered erectile function (PHEs or BTB erections).
  • Baseline ISD and 24-month EFD predicted 24-month ISD, but baseline ISD was the sole predictor for men with BTB erections.

Conclusions:

  • Restoration of erectile function alone does not ensure restoration of intercourse satisfaction after RP.
  • Sexual dysfunction significantly impacts intercourse satisfaction post-RP.
  • Psychological support and improved patient counseling are crucial for managing post-RP expectations and needs.