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Updated: Feb 7, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
Published on: September 18, 2013
STAMPEDEing metastatic prostate cancer: CHAARTing the LATITUDEs
Aditya Prakash Sharma1, Ravimohan S Mavuduru1, Girdhar Singh Bora1
1Department of Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Abstract:
With the emergence of recent landmark trials, the treatment for hormone-sensitive metastatic prostate cancer (hsMPC) is changing from androgen deprivation therapy (ADT) alone to combination therapy. Both, docetaxel chemotherapy and abiraterone in addition to ADT have been extensively studied in well-conducted randomized controlled trials and were shown to improve outcomes. However, this paradigm shift in the treatment has also raised some queries. This mini review reflects upon the four landmark trials and tries to provide some perspective about the decision-making process for the patients with hsMPC.
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