Related Experiment Video
Updated: Feb 7, 2026

09:29
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
18.9K
Propranolol and breast cancer-a work in progress
Pan Pantziarka1,2, Brad A Bryan3, Sergio Crispino1
1Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Ecancermedicalscience
|July 24, 2018
Summary
The common drug propranolol shows promise as an anti-cancer treatment, especially for breast cancer. Its ability to stop cancer spread (metastasis) suggests potential use around surgery.
Area of Science:
- Oncology
- Pharmacology
- Translational Medicine
Background:
- Propranolol, a non-selective beta-blocker, is being investigated for novel anti-cancer applications.
- Emerging evidence, including human data, highlights its potential mechanisms of action in breast cancer.
Discussion:
- Recent studies indicate propranolol possesses anti-metastatic properties.
- These findings support further clinical investigation into propranolol's efficacy against cancer spread.
Key Insights:
- Propranolol demonstrates anti-metastatic activity relevant to breast cancer.
- Multiple mechanisms of action are suggested by current research.
Outlook:
- Clinical investigation of propranolol as a perioperative therapy for breast cancer is warranted.
- Further research may establish propranolol as a repurposed anti-cancer agent.
Related Concept Videos
mTOR Signaling and Cancer Progression
4.8K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
4.8K
Tumor Progression
7.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
Cancer
54.4K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.4K
What is Cancer?
14.5K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.5K
Cancer Vaccines
1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K

