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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Related Experiment Video

Updated: Jan 6, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

New developments in brain metastases.

Anna S Berghoff¹, Matthias Preusser²

¹Department of Medicine I, Medical University of Vienna, Vienna, Austria Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

Therapeutic Advances in Neurological Disorders

|July 24, 2018

Summary

This summary is machine-generated.

New treatments for brain metastases (BM) focus on improving survival. Advances in local therapies and systemic treatments, including targeted therapies and immune-checkpoint inhibitors, offer new hope for patients with BM.

Keywords:

ALK translocation EGFR mutation anti-HER2 therapy brain metastases immune-checkpoint inhibitors targeted therapies

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Last Updated: Jan 6, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

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Published on: August 2, 2022

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

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Published on: June 7, 2020

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

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Published on: February 8, 2017

Area of Science:

Neuro-oncology
Radiation Oncology
Medical Oncology

Background:

Brain metastases (BM) represent a significant clinical challenge with poor prognoses.
Limited clinical trials have addressed the heterogeneity of BM patient populations.
Existing treatments for BM often involve significant side effects.

Purpose of the Study:

To review recent advancements in local and systemic therapies for brain metastases.
To highlight novel approaches in managing BM patients.
To discuss the evolving landscape of BM treatment strategies.

Main Methods:

Literature review of recent clinical trials and therapeutic developments in BM.
Analysis of new indications and applications for local therapies like stereotactic radiosurgery and whole-brain radiotherapy (WBRT).
Evaluation of systemic therapy approaches, including targeted mutations and immune-checkpoint inhibitors.

Main Results:

Refined indications for stereotactic radiosurgery and whole-brain radiotherapy (WBRT), including hippocampal sparing WBRT, aim to reduce side effects.
Systemic therapies show promising intracranial efficacy, especially in patients with targetable mutations.
Immune-checkpoint inhibitors demonstrate efficacy in melanoma and non-small cell lung cancer BM.

Conclusions:

Recent developments offer improved therapeutic strategies for brain metastases.
Combining local and systemic treatments may enhance outcomes for BM patients.
Further research is needed to optimize treatment paradigms for this heterogeneous population.