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Models of Bone Metastasis
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Bone cement allocation analysis in artificial cancellous bone structures.

Ivan Zderic1, Philipp Steinmetz1, Lorin M Benneker2

  • 1AO Research Institute Davos, Davos, Switzerland.

Journal of Orthopaedic Translation
|July 24, 2018
PubMed
Summary
This summary is machine-generated.

This study simulated bone cement injection into artificial bone, finding that leakage paths and bone marrow significantly affected cement distribution. Stepwise injection was ineffective in preventing leakage due to short waiting times.

Keywords:
bone cement leakageflow behaviourfoam modelpreoperative planningvertebroplasty

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Area of Science:

  • Biomaterials science
  • Medical engineering
  • Orthopedic surgery

Background:

  • Vertebroplasty carries risks of cement leakage, a serious adverse event.
  • Preoperative planning of cement filling can mitigate these risks.
  • Understanding bone cement flow behavior is crucial for improved planning.

Purpose of the Study:

  • To investigate bone cement distribution in artificial inhomogeneous cancellous bone.
  • To simulate a stepwise injection procedure to analyze cement flow.

Main Methods:

  • Stepwise injection of four colored cement portions into aluminum foam models with simulated leakage paths.
  • High-resolution imaging and radial grid analysis of cement distribution.
  • Measurement of cement viscosity during simulated injections.

Main Results:

  • No interfusion between differently colored cement portions was observed.
  • Cement distribution was influenced by simulated leakage paths and bone marrow.
  • Viscosity increased significantly from the first to the last injection portion.

Conclusions:

  • Simulated leakage paths and bone marrow were key factors affecting cement distribution uniformity.
  • The medium viscosity of the cement contributed to overall uniform distribution.
  • The 45-second waiting time in stepwise injection was insufficient to prevent cement leakage.