[FUNCTIONAL PARAMETERS OF BLOOD CIRCULATION IN FIRST THREE MONTHS AFTER RADIOFREQUENCY ABLATION OF ATRIAL...

The purpose of the study was to evaluate functional parameters of blood circulation in first 3 months after radiofrequency ablation of atrial fibrillation and atrial flutter. The study included 113 patients aged 59.3±10.1 years, after radiofrequency ablation (RFA) with pulmonary veins isolation (PVI) for atrial fibrillation (AF), RFA of cava-tricuspid isthmus (CTI) for atrial flutter (AFl), or combined RFA PVI and CTI. Presence of arrhythmia recurrence episodes, blood pressure (BP) levels, electrocardiographic and echocardiographic indices were assessed before RFA, in acute postoperative period (3-5 days) and 3 months after RFA in the groups of AF, AFl, and AF/AFl combination. In acute postoperative period, arrhythmia recurrence of was most often recorded in the AF/AFl group, less often in groups of isolated AF and AFl, 3 months later - the frequency of recurrence decreased in all groups, but the largest remained in group of combined AF/AFl. In first 3 months after RFA of AF a decreased heart rate (HR), right atrium (RA) and ventricle (RV) size, an increased QTc interval duration and BP; after RFA of AFl - a decreased HR, end-diastolic volume (EDV) and RA; and after RFA of AF/AFl - a decreased ejection fraction (EF), an increased BP, QTc interval duration, and the end-systolic volume (EDV) were recorded. The results showed that effectiveness of RFA of isolated AF and AFl is higher than RFA of combined AF/AFl in the first 3 months after the procedure. Isolated AF and AFl after RFA were associated with BP and QTc interval duration increase, HR, EDV, RA and RV decrease; combined RFA of AF and AFl - with BP, QTc interval duration and ESV increase and left ventricular EF decrease.