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Why a P-Value is Not Enough.

Federico Solla1, Antoine Tran2, Domenico Bertoncelli3

  • 1Department of Orthopaedic Surgery.

Clinical Spine Surgery
|July 24, 2018
PubMed
Summary
This summary is machine-generated.

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Statistical significance requires more than a P-value. Reporting effect sizes and confidence intervals (CI) alongside P-values provides a more complete analysis of scientific data.

Area of Science:

  • Biostatistics
  • Medical Research
  • Scientific Publication

Background:

  • P-values are commonly used to determine statistical significance (P<0.05).
  • However, P-values alone do not fully represent the magnitude or clinical relevance of findings.
  • Publications often require additional statistical parameters for comprehensive data analysis.

Purpose of the Study:

  • To present P-values, confidence intervals (CI), and common effect sizes (e.g., Cohen's d, odds ratio) in a simplified manner.
  • To emphasize the importance of these additional parameters for robust scientific interpretation.

Main Methods:

  • Explanation of P-value interpretation: probability of results occurring by chance.
  • Definition and interpretation of confidence intervals (CI), including the significance threshold.

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  • Introduction to effect sizes as quantitative measures of association strength.
  • Main Results:

    • P-values indicate statistical significance but not the size of an effect.
    • Confidence intervals provide a range for the true value, with significance indicated by exclusion of the null hypothesis.
    • Low effect sizes, even with P<0.05, may lack clinical significance.

    Conclusions:

    • Scientific publications necessitate reporting of effect sizes and CIs beyond P-values.
    • Including these parameters ensures a more complete, honest, and useful interpretation of research findings.
    • This approach enhances the overall quality and impact of scientific communication.