Long-term recurrent bleeding risk after endoscopic therapy for definitive colonic diverticular bleeding: band

Naoyoshi Nagata1, Naoki Ishii2, Mitsuru Kaise3

  • 1Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo, Japan.

Insights

Endoscopic band ligation shows a lower 1-year recurrent bleeding risk for colonic diverticular bleeding (CDB) compared to clipping. This suggests band ligation offers better long-term outcomes for managing CDB.

Area of Science:

  • Gastroenterology
  • Endoscopic interventions
  • Gastrointestinal bleeding

Background:

  • Limited prospective studies evaluate long-term outcomes of endoscopic therapy for colonic diverticular bleeding (CDB).
  • Recurrent bleeding risk after endoscopic treatment for CDB requires further elucidation.

Purpose of the Study:

  • To compare the 1-year recurrent bleeding risk of endoscopic band ligation versus clipping for definitive CDB.
  • To evaluate long-term outcomes of endoscopic therapies for CDB based on stigmata of recent hemorrhage (SRH).

Main Methods:

  • Prospective enrollment of patients hospitalized for acute lower GI bleeding.
  • High-resolution colonoscopy with water-jet visualization for SRH.
  • First-line treatment using endoscopic band ligation or clipping, followed by prospective follow-up.

Main Results:

  • 1-year recurrent bleeding probability was significantly lower with band ligation (11.5%) versus clipping (37.0%).
  • No statistical difference in baseline characteristics or follow-up duration between groups.
  • Left colon location was an independent predictor for recurrent bleeding in the ligation group.

Conclusions:

  • Endoscopic band ligation demonstrates superior long-term outcomes compared to clipping for definitive CDB treatment.
  • Band ligation may be more effective due to complete diverticulum elimination, reducing recurrence.
  • CDB recurrence can occur at the same diverticulum short-term or different diverticula long-term.
Abstract

Related Concept Videos

Bleeding in Fresh Concrete01:22

Bleeding in Fresh Concrete

Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete.
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
595
Band Theory02:35

Band Theory

When two or more atoms come together to form a molecule, their atomic orbitals combine and molecular orbitals of distinct energies result. In a solid, there are a large number of atoms, and therefore a large number of atomic orbitals that may be combined into molecular orbitals. These groups of molecular orbitals are so closely placed together to form continuous regions of energies, known as the bands.
The energy difference between these bands is known as the band gap.
Conductor, Semiconductor,...
17.2K
Definite Integral01:29

Definite Integral

Consider a real-valued function defined on a closed interval. One of the fundamental objectives in calculus is to determine the area under the graph of such a function. When an exact computation is not readily available, this area can be estimated by dividing the interval into a finite number of equal subintervals. Each subinterval corresponds to a rectangle whose width is the length of the subinterval and whose height is determined by the value of the function at a selected point within that...
78
The Colonization of Land02:22

The Colonization of Land

Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
37.7K