[Augmentation by dilution of the effect of PVP iodine on poliomyelitis virus type I]

The influence of dilution of povidone-iodine solutions on virucidal activity against poliovirus type 1 was investigated. After exposure to different concentrations of povidone-iodine, the reduction in virus titer was determined after separating the antiseptic by gel filtration. Diluted preparations (0.5 and 0.25%) achieved a greater reduction in virus titer (10(5) in one hour) than the 5% stock solution (10(3)). Moreover, dilute solutions exhibited a faster virucidal activity.