Complications associated with diagnostic cerebral angiography: A retrospective analysis of 644 consecutive cerebral angiographic cases
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Updated: Feb 7, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Jie Shen1, Mohan Karki1, Tao Jiang1
1Department of Neurosurgery, Neurovascular Diseases Research Center, Second Affiliated Hospital Anhui Medical University, Hefei, Anhui Province, People's Republic of China.
Insights
Modern cerebral angiography is generally safe, with rare but serious complications like groin hematoma and neurologic deficits. Careful patient selection and training can minimize risks associated with this diagnostic procedure.
Area of Science:
- Neurology
- Radiology
- Vascular Medicine
Background:
- Cerebral angiography is a key diagnostic tool for cerebrovascular diseases.
- Assessing complication rates is crucial for patient safety and procedural refinement.
Purpose of the Study:
- To evaluate the incidence and types of minor and major complications in modern cerebral angiography.
- To identify risk factors and outcomes associated with cerebral angiography procedures.
Main Methods:
- Retrospective analysis of 644 consecutive cerebral angiographic cases.
- Detailed review of patient records focusing on documented complications.
Main Results:
- Groin hematoma (1.55%) was the most frequent complication.
- Neurologic complications occurred in 0.62% of cases, including one permanent hemiplegia (0.16%).
- Contrast-induced nephropathy (5%) and one death from air emboli (0.16%) were also reported.
Conclusions:
- Neurologic complications from cerebral angiography are infrequent but significant.
- Careful patient selection and enhanced training are vital for minimizing procedural risks.
- While risks are low, severe outcomes like permanent disability or death cannot be entirely eliminated.
Aim:
This study was conducted to evaluate complications (minor and major) that occurred in patients who underwent modern cerebral angiography.
Materials And Methods:
A retrospective assessment of 644 consecutive cerebral angiographic cases was undertaken with specific emphasis on complications.
Results:
The most common complication of diagnostic cerebral angiography was groin hematoma seen in 10 (1.55%) patients. One patient had complications arising from the development of a femoral artery pseudoaneurysm. Neurologic complications occurred in 4 (0.62%) cases. Three (0.47%) cases had transient complications which resolved completely within 24 h. One patient (0.16%) was left with permanent hemiplegia. There were 6 (5%) cases of contrast-induced nephropathy out of the 120 cases in whom subarachnoid hemorrhage had occurred and who possessed complete data of kidney function tests. Five of them were reversible, and one was permanent. One patient (0.16%) died from air emboli.
Conclusions:
Neurologic complications following cerebral angiography are rare but must be minimized by careful case selection and training. Although the risk is small, complications such as permanent disability or even death cannot be completely obviated.
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