Related Experiment Video
Updated: Feb 7, 2026

Investigating Migraine-Like Behavior Using Light Aversion in Mice
Published on: August 11, 2021
Paediatric migraine: evidence-based management and future directions.
Serena L Orr1, Marielle A Kabbouche2,3, Hope L O'Brien2,3
1Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. serena.orr@cchmc.org.
Paediatric migraine management requires a biopsychosocial approach with timely acute treatments and psychological interventions. Preventive strategies, including daily pill-taking, may aid management, but further research is needed.
Area of Science:
- Pediatric Neurology
- Pain Management
- Psychology
Background:
- Migraine is a common and disabling condition in children and adolescents.
- Effective early treatment is crucial for improving outcomes in this population.
- A biopsychosocial approach integrating multimodal care is recommended.
Purpose of the Study:
- To review current effective management strategies for paediatric migraine.
- To discuss the role of pharmacological, psychological, and self-management interventions.
- To highlight the need for further research in migraine prevention for this age group.
Main Methods:
- Review of recent findings on paediatric migraine treatment.
- Analysis of interdisciplinary multimodal care components.
- Evaluation of pharmacological and non-pharmacological preventive interventions.
Main Results:
- Effective acute treatment includes NSAIDs and triptans.
- Psychological interventions like CBT and biofeedback are key components.
- The efficacy of current preventive pharmacological/nutraceutical options is unclear, but placebo effects are noted.
Conclusions:
- A multimodal, biopsychosocial approach is most effective for paediatric migraine.
- Daily pill-taking interventions may be considered for prevention alongside non-pharmacological methods.
- Further research is essential to clarify preventive strategies and placebo response mechanisms.
Related Concept Videos
The Evidence for Evolution
Directing Effect of Substituents: meta-Directing Groups
Crossed Aldol Reaction Using Strong Bases: Directed Aldol Reaction
Tonsillitis II: Management
Directing Effect of Substituents: ortho–para-Directing Groups
Impression Management Techniques I: Managing Appearances

