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Pediatric Crohn's Disease in Bahrain
Hasan M Isa1, Afaf M Mohamed2, Halima E Al-Jowder1
1Pediatric Department, Salmaniya Medical Complex, Arabian Gulf University, Manama, Bahrain.
Oman Medical Journal
|July 25, 2018
Summary
Pediatric Crohn's disease (CD) incidence is rising in Bahrain, with clinical features similar to global trends. This study details CD epidemiology, presentation, and management in Bahraini children.
Area of Science:
- Pediatric Gastroenterology
- Inflammatory Bowel Disease Research
- Epidemiology
Background:
- Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with increasing global prevalence.
- Understanding the epidemiology and clinical characteristics of pediatric CD is crucial for effective management.
Purpose of the Study:
- To investigate the epidemiology, clinical presentations, diagnostic and therapeutic strategies, and outcomes of pediatric Crohn's disease in Bahrain.
- To establish baseline data for pediatric CD in the region.
Main Methods:
- Retrospective review of medical records of pediatric patients diagnosed with CD from 1984 to 2017.
- Analysis of demographic data, clinical features, diagnostic findings, treatments, and patient outcomes.
- Calculation of annual incidence and cumulative prevalence rates.
Main Results:
- Out of 108 pediatric IBD cases, 51 (47.2%) were diagnosed with CD.
- Annual incidence showed a significant rise over three decades (p=0.0001), with a prevalence of 9.32 per 100,000 children.
- Common symptoms included abdominal pain and weight loss; terminal ileum and colon were frequently involved.
Conclusions:
- Pediatric Crohn's disease in Bahrain exhibits clinical characteristics comparable to international and regional data.
- The study highlights a concerning increase in pediatric CD incidence over time in Bahrain.