Reactions in NMR Tubes as Key Weapon in Rational Drug Design
1Department of Chemistry, Laboratory of Organic Chemistry, National and Kapodistrian University of Athens, Athens, Greece. doudaniotis@yahoo.gr.
Abstract:
NMR spectroscopy is a powerful technique suitable for obtaining detailed structural and dynamic data at atomic resolution. Progress in NMR instrumentation has led the scientific community to produce novel techniques which provide valuable information to resolve demanding and crucial questions of molecular biology and rational drug design. This chapter outlines the progress of NMR spectroscopy in the rational drug design. In addition, it offers an example of a reaction in NMR tube for achieving rational drug design.
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