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Updated: Feb 7, 2026

Murine Dermal Fibroblast Isolation by FACS
Published on: January 7, 2016
The development of a treatment pathway for dermal regenerative matrix (DRM)
Claudia Malic1, Sarvesh Logsetty2, Anthony Papp3
1Department of Surgery, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Abstract:
The process of standardising burn care and creating protocols within burn centres has, at its core, evidence-based practice principles combined with the clinical experiences of burn care specialists. Although protocols and pathways have been created for certain topics of burn care, they tend to be tailored to the local individual needs of each burn centre, which is a limiting factor for consideration of larger/nationwide approaches. In order to continue to improve the short and long term outcomes after burn injuries, such as increasing the survival rate, reduction in the incidence of sepsis and organ failure, and improving wound healing and scarring, more generalised care pathways combining the recommendations of a nationwide working group of burn care specialists should be created around the topics of interest to ultimately improve patients' outcomes. We describe the steps put in place in Canada to design and adopt a nationwide protocol from a single burn centre on the topic of wound healing and dermal substitutes as the initial exemplary process. This report summarizes the Canadian experience for this type of initiative, which can be used as framework for developing additional guidelines/protocols in other relevant burn care related topics in Canada or other countries.
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