[Renal Cancer after Spontaneous Rupture Successfully Treated with Low-Dose Oral UFT - A Case Report]

A 94-year-old man, who had been diagnosed with a 5.7 cm renal carcinoma 4 months before and followed up with no therapy, presented with a 3-day history of macrohematuria. Abdominal CT revealed an enlarged right renal tumor, tumoral hemorrhage, and a right retroperitoneal hematoma. Therefore, spontaneous rupture of the renal carcinoma was diagnosed. As his general condition was not serious, he rejected aggressive treatments such as nephrectomy. Instead, he chose treatment with an antineoplastic drug, UFT, which was started orally at a dose of 200mg/day. Under hospitalization, his clinical course was uneventful, and he was discharged 14 days later. Follow-up CT films showed that the size of the tumor gradually decreased. Sixteen months after UFT administration, a CT displayed a right renal tumor with an 86% decrease in size compared with the tumor size when first diagnosed.