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Challenges and Opportunities in the Management of Onychomycosis

Julia K Christenson1, Gregory M Peterson2, Mark Naunton3

  • 1Faculty of Health, University of Canberra, Bruce, Canberra, ACT 2601, Australia. Julia.Christenson@canberra.edu.au.

Journal of Fungi (Basel, Switzerland)
|July 26, 2018
PubMed

Insights

Onychomycosis, a common fungal nail infection, is hard to treat. New research explores alternative therapies like natural treatments and physical methods, but more trials are needed for recommendations.

Area of Science:

  • Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Onychomycosis is a prevalent fungal nail infection, primarily caused by dermatophytes.
  • Treatment challenges include deep fungal location, long duration, poor adherence, and high recurrence rates.
  • Current topical and systemic therapies show limited efficacy, driving interest in alternative treatments.

Purpose of the Study:

  • To review and assess alternative treatment modalities for onychomycosis.
  • To highlight emerging therapies beyond conventional treatments.
  • To identify the need for further research in onychomycosis management.

Main Methods:

  • Literature review of emerging treatments for onychomycosis.
  • Analysis of preliminary research on natural therapies, physical treatments, and combination therapies.
  • Assessment of the current evidence base for novel interventions.

Main Results:

  • Alternative therapies including natural products, physical methods, and combination approaches show promise.
  • Research in these areas is largely in preliminary stages.
  • Efficacy of novel treatments requires further validation.

Conclusions:

  • Alternative treatments offer potential for onychomycosis management.
  • Robust, large-scale randomized controlled trials are essential.
  • Evidence is needed to support clinical recommendations for novel therapies.
Keywords:
alternative treatmentcombination therapyfungiinfectionnailonychomycosistreatment

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