Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Connective Tissues01:17

Functions of Connective Tissues

16.9K
Connective tissues perform a broad range of functions in the body. Their primary function is to connect and link different tissues in the body and act as packaging material between tissues. The areolar tissue, a connective tissue prototype, commonly cements various tissue types in diverse body organs. In contrast, adipose tissue cushions internal organs while insulating the body from heat loss.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
16.9K
Structural Protein Function01:56

Structural Protein Function

30.0K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
30.0K
Structural Protein Function01:56

Structural Protein Function

3.3K
3.3K
Fruit Development, Structure, and Function01:58

Fruit Development, Structure, and Function

25.4K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.4K
Structure and Function of Erythrocytes01:29

Structure and Function of Erythrocytes

6.0K
There are between 4.2 and 6 million erythrocytes, also known as red blood cells, in every microliter of blood. These cells are small, flattened biconcave discs with centers that are depressed.
The erythrocyte plasma membrane is associated with proteins such as spectrin, which forms a flexible cytoplasmic meshwork. This meshwork allows erythrocytes to twist, turn, become cup-shaped, and regain their biconcave shape as they pass through narrow capillaries. Additionally, erythrocytes can form...
6.0K
Structure and Function of Platelets01:18

Structure and Function of Platelets

3.6K
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between carotid arterial wall components and brain atrophy in hypertensive individuals.

Vascular medicine (London, England)·2026
Same author

Safety in epilepsy surgery: a multicenter analysis of surgery-related complications and seizure outcome in 1167 cases of mesial temporal lobe epilepsy.

Journal of neurosurgery·2026
Same author

Appraising Asymmetric Temporal Deformity: A Three-Dimensional Imaging-Based Panel and Morphometric Outcome Study.

The Journal of craniofacial surgery·2026
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Shared genetic architecture of brain age gap across 30 cohorts worldwide.

medRxiv : the preprint server for health sciences·2026
Same author

Unveiling Epileptic Networks: Motif Synchronization for Interictal Spike Localization.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Combined biofeedback and vestibular rehabilitation therapy for vestibular migraine: clinical efficacy and neurobiochemical correlates.

Frontiers in neurology·2026
Same journal

Effects of transitional care interventions on rehospitalization, functional outcomes, and quality of life in stroke survivors: an updated systematic review and meta-analysis of randomized controlled trials.

Frontiers in neurology·2026
Same journal

Endovascular thrombectomy in selected patients with active cancer and thrombocytopenia: outcomes under an institutional platelet transfusion practice.

Frontiers in neurology·2026
Same journal

Modified small vessel disease score as the top predictor of stroke outcome after thrombectomy: a CT-based machine learning study.

Frontiers in neurology·2026
Same journal

Correction: Novel surrogate markers of CNS inflammation in CSF in the diagnosis of autoimmune encephalitis.

Frontiers in neurology·2026
Same journal

Real-world 24-month pain outcomes of disk percutaneous ablation and extraction versus Disc-FX nucleoplasty for lumbar discogenic pain and contained lumbar disk herniation: a single-center retrospective cohort study.

Frontiers in neurology·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

15.4K

Differences in Cortical Structure and Functional MRI Connectivity in High Functioning Autism.

Alessandra M Pereira1,2, Brunno M Campos1, Ana C Coan1

  • 1Neuroimaging Laboratory, School of Medical Sciences, The Brazilian Institute of Neuroscience and Neurotechnology, University of Campinas, Campinas, Brazil.

Frontiers in Neurology
|July 26, 2018
PubMed
Summary
This summary is machine-generated.

Autism spectrum disorder (ASD) is linked to brain structure and connectivity differences. These alterations in the default mode network may explain core ASD social and communication challenges.

Keywords:
MRIautism spectrum disorderscortical thicknessdefault mode network (DMN)functional connectivitysocial communicationstereotyped behavior

More Related Videos

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging
11:28

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Published on: June 30, 2018

12.3K
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
12:09

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Published on: August 5, 2014

18.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

15.4K
Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging
11:28

Concurrent EEG and Functional MRI Recording and Integration Analysis for Dynamic Cortical Activity Imaging

Published on: June 30, 2018

12.3K
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
12:09

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

Published on: August 5, 2014

18.5K

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Neuroimaging

Background:

  • Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting communication and social interaction.
  • Understanding the neural underpinnings of ASD is crucial for developing targeted interventions.

Purpose of the Study:

  • To investigate system-level brain alterations in high-functioning autism using functional connectivity (FC) and multimodal morphometry.
  • To explore the relationship between structural brain changes and functional connectivity within the default mode network (DMN) in adolescents and young adults with ASD.

Main Methods:

  • Compared 22 adolescents and young adults with high-functioning ASD to 29 age- and IQ-matched healthy controls.
  • Utilized multimodal morphometry to assess gray matter volume, cortical thickness, surface area, and gyrification.
  • Examined functional connectivity (FC) within the default mode network (DMN) using neuroimaging techniques.

Main Results:

  • ASD group showed gray matter reduction, decreased cortical thickness, and larger cortical surface areas in key brain regions (e.g., cingulate, temporal lobes, amygdala).
  • Increased gyrification was observed in visual memory and sensorimotor DMN regions, particularly in the left hemisphere.
  • Altered DMN connectivity included decreased connectivity between the posterior cingulate cortex and executive control regions, and increased FC between the anteromedial prefrontal cortex and sensorimotor regions.

Conclusions:

  • Structural and connectivity abnormalities in the DMN are present in high-functioning ASD.
  • Specific cortical thickness reductions correlated with social and communication impairments, as measured by the Autism Diagnostic Interview-Revised (ADI-R).
  • These findings suggest that combined structural and functional brain alterations contribute to core ASD behaviors and warrant further investigation.