Related Experiment Video
Updated: Feb 7, 2026

Intravitreal Injections in the Ovine Eye
Published on: July 5, 2022
Partial thickness sclerectomy and intravitreal anti-VEGF therapy for intractable uveal effusion syndrome
Jing Guo1,2,3, Xiaoguang Cao1,2, Xiaoxin Li4,5
1Department of Ophthalmology, Peking University People's Hospital, Xizhimen South Street 11, Beijing, 100044, China.
Purpose:
To report a case series of three patients with intractable uveal effusion syndrome (UES), treated with partial thickness sclerectomy and intravitreal anti-VEGF therapy.
Methods:
Three patients with intractable UES were included. All patients underwent intravitreal anti-VEGF therapy to facilitate resolution of uveal effusion. The concentrations of IL-1β, IL-6, IL-8, IL-10, IL-12p70, TNF and VEGF in aqueous humor were measured.
Results:
After the last intravitreal injection, all three eyes had total resolution of the chorioretinal detachment or subretinal fluid. One eye experienced improvement in visual acuity. All patients were free from recurrence during the follow-up period. Aqueous IL-6, IL-8 and VEGF concentrations were elevated in all cases.
Conclusions:
Our current data provided the evidence that VEGF was increased in eyes with intractable UES and anti-VEGF therapy was effective, suggesting that partial thickness sclerectomy and intravitreal anti-VEGF therapy could be a new choice for intractable UES.
Related Concept Videos
Behavior of Gas Molecules: Molecular Diffusion, Mean Free Path, and Effusion
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Partial Fractions
Gene Therapy
Mixtures of Gases: Dalton's Law of Partial Pressures and Mole Fractions

