Related Experiment Video
Updated: Feb 7, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve surgery for acute papillary muscle rupture
Ibrahim Sultan1,2, Edgar Aranda-Michel1, Thomas G Gleason1,2
1Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
Papillary muscle rupture (PMR) after heart attack is rare. Mitral valve surgery for acute PMR showed acceptable operative mortality and good longer-term outcomes in this study.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardiovascular Research
Background:
- Papillary muscle rupture (PMR) is a rare but serious complication following myocardial infarction.
- Acute PMR necessitates urgent intervention to manage severe mitral regurgitation.
Purpose of the Study:
- To review the outcomes of mitral valve surgery for acute papillary muscle rupture.
- To assess operative morbidity, mortality, and long-term results following PMR repair.
Main Methods:
- Retrospective review of patients undergoing emergent mitral valve surgery for acute PMR (2011-2017).
- Analysis of operative outcomes including morbidity, mortality, reoperation, and readmission.
- Evaluation of long-term survival and valve-related events.
Main Results:
- 24 patients (1.0%) underwent surgery for PMR out of 2479 mitral valve surgeries.
- Operative mortality was 12.5% (3 patients), with an observed-to-expected mortality ratio of 0.71.
- Three-year outcomes included 21.1% mortality, 5.0% reoperation, and 45.4% readmission.
Conclusions:
- Early surgical intervention for PMR can lead to acceptable short-term and long-term results.
- Mitral valve surgery provides a viable treatment option for patients with acute PMR.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Valve Prolapse III: Nursing Management
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Mitral Stenosis I: Introduction

