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Gastric gas dynamics in healthy humans
N Caballero1,2, I Marin1,2, J Serra1,2
1Motility and Functional Gut Disorders Unit, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain.
Neurogastroenterology and Motility
|July 26, 2018
Summary
Healthy humans primarily evacuate gastric gas through the intestines, but belching is a compensatory mechanism. This study investigated gastric gas transit and its link to abdominal symptoms in healthy individuals.
Area of Science:
- Gastroenterology
- Human Physiology
Background:
- The stomach manages daily gas increments via propulsion to the small bowel or belching.
- Understanding gastric gas transit is crucial for managing abdominal discomfort.
Purpose of the Study:
- To evaluate the transit of free gastric gas in healthy humans.
- To determine the relationship between gastric gas transit and abdominal symptoms.
Main Methods:
- 24 healthy volunteers received gastric gas infusions at varying rates (0, 25, 50, 100 mL/min) up to 1500 mL.
- Belching, rectal gas evacuation, and abdominal perception were continuously monitored for 90 minutes.
Main Results:
- Gastric gas infusion significantly increased rectal gas evacuation and belching compared to sham infusion.
- A negative correlation was observed between rectal gas evacuation and belching frequency.
- Individuals who primarily evacuated gas rectally reported more severe abdominal symptoms than those who belched more frequently.
Conclusions:
- The stomach efficiently adapts to gas variations through a balance of belching and distal gas emptying.
- While most gastric gas is emptied distally, belching serves as a mechanism to improve gas tolerance in certain situations.
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