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Updated: Feb 7, 2026

Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis
Published on: May 16, 2025
IVTH BRAZILIAN CONSENSUS CONFERENCE ON HELICOBACTER PYLORI INFECTION.
Luiz Gonzaga Vaz Coelho1, James Ramalho Marinho2, Robert Genta3
1Universidade Federal de Minas Gerais, Instituto Alfa de Gastroenterologia, Belo Horizonte, MG, Brasil.
Updated guidelines for managing Helicobacter pylori infection in Brazil were established. This fourth consensus meeting involved experts reviewing diagnosis, treatment, and the link between H. pylori and gastric cancer.
Area of Science:
- Gastroenterology and Infectious Diseases
- Microbiology
- Public Health
Background:
- The III Brazilian Consensus Conference on Helicobacter pylori infection in 2012 highlighted the need for updated management guidelines.
- Significant advancements in understanding H. pylori infection necessitated a fourth consensus meeting.
Framework:
- The Núcleo Brasileiro para Estudo do Helicobacter pylori e Microbiota (NBEHPM) convened 26 experts in Bento Gonçalves, Brazil, in August 2017.
- Participants reviewed epidemiology, diagnosis, treatment, and the association of H. pylori with dyspepsia, microbiota changes, and gastric cancer.
Implementation:
- Delegates were divided into four groups: Epidemiology and Diagnosis; Dyspepsia, Intestinal Microbiota, and Other Affections; Gastric Cancer; and Treatment.
- Statements were developed through literature review, group discussion, and two rounds of voting, with an 80% consensus index adopted.
Implications:
- The consensus provides current evidence-based recommendations for managing H. pylori infection in the adult Brazilian population.
- Updated guidelines are crucial for optimizing H. pylori treatment strategies and addressing associated health concerns, including gastric cancer.
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