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Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions
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Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study

Robert Fong1, Lingzhi Wang, James P Zacny

  • 1From the Departments of Anesthesia and Critical Care (R.F., L.W., J.P.Z., S.K., J.L.A., Z.X.) Neurobiology (A.P.F.), University of Chicago, Chicago, Illinois the Department of Anesthesia, Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (L.W.) the Cancer Center (J.P.Z.) the College of Medicine (S.K.), University of Illinois at Chicago, College of Medicine, Chicago, Illinois.

Anesthesiology
|July 26, 2018
PubMed
Summary

Caffeine significantly speeds up recovery from isoflurane anesthesia in healthy males. This study found that intravenous caffeine reduced anesthesia emergence time by 42% with no adverse effects.

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