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Updated: Feb 7, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
[Quantitative analysis based on three-dimensional stereophotogrammetry in the observation of curative effect of
Objective:
To observe the curative effect of botulinum toxin A on masseter hypertrophy using three-dimensional stereophotogrammetry.
Methods:
46 cases with masseter hypertrophy (92 masseters) who received botulinum toxin A injection were enrolled from May 2013 to August 2014.Data were collected before and 3,6 and 9 months after injection.
Results:
The efficacy of botulinum toxin A in reducing the volume of the lower face has been proven by MAS 3D.3 and 6 months after injection, the volume reduction were measured as 7.23 %,2.15% respectively (P < 0.05).The coefficients between middle and lower thirds of the face showed an increase compatible with thinning of the lower face with statistical significance at 3 months follow up. The increase percentage was measured by MAS 3D as 40.21% between pre-and post-injection (P < 0.05),and the increase percentage was 21.03% at 6 months follow up (P < 0.05).While 9 months after injection,the value was insignificant comparing to pretreatment at 9 months.
Conclusions:
Three-dimensional stereophotogrammetry provides a safe effective and direct way to observe masseter hypertrophy.
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