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Toddler With Intermittent Abnormal Behavior: Is It Isoniazid-Induced Psychosis?
Indar Kumar Sharawat1, Lesa Dawman2
1From the Department of Paediatrics, VMMC & Safdarjung Hospital.
Abstract:
Psychosis is a state of altered behavior and mentation, and it is rarely reported in preschool children. Isoniazid is a commonly used drug in the treatment and prophylaxis of tuberculosis. It may cause psychosis in overdose but rarely with usual recommended doses. We report a case of drug-induced psychosis secondary to isoniazid intake in a 3-year-old child. She developed intermittent abnormal behavior for 2 weeks after intake of isoniazid. Drug-induced psychosis was a possibility, and the responsible drug was stopped. She improved following the withdrawal of isoniazid.
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