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Related Experiment Video

Updated: Feb 7, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
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Corneal densitometry in high myopia.

Jing Dong1, Yaqin Zhang2, Haining Zhang2

  • 1Department of Ophthalmology, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, People's Republic of China.

BMC Ophthalmology
|July 27, 2018
PubMed
Summary

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Highly myopic corneas exhibit lower corneal densitometry values compared to normal corneas, indicating reduced light backscatter. This finding was consistent across various corneal zones and depths in Scheimpflug tomography analysis.

Area of Science:

  • Ophthalmology
  • Corneal Imaging
  • Biomedical Optics

Background:

  • Corneal densitometry quantifies light scattering within the cornea.
  • Scheimpflug tomography is an advanced imaging technique for corneal analysis.
  • Understanding corneal densitometry differences in myopia is crucial for refractive error assessment.

Purpose of the Study:

  • To compare corneal densitometry values between normal and highly myopic (HM) eyes.
  • To evaluate differences in densitometry across corneal layers and zones using Scheimpflug tomography.

Main Methods:

  • Corneal densitometry was performed on 100 normal and 100 HM eyes using the Pentacam Scheimpflug system.
  • Densitometry was analyzed in annular zones (0-2 mm, 2-6 mm, 6-10 mm, 10-12 mm) and corneal depths (anterior, central, posterior).
Keywords:
Corneal densitometryHigh myopiaNormalScheimpflug

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Main Results:

  • Highly myopic eyes showed significantly lower total corneal thickness densitometry in all measured annuli compared to normal eyes.
  • Lower anterior layer densitometry was observed in HM eyes within the 2-6 mm and 6-10 mm zones.
  • HM eyes exhibited lower central and posterior layer densitometry across all annuli.

Conclusions:

  • Corneal densitometry maps indicate reduced light backscatter in most regions of the highly myopic cornea.
  • These findings suggest structural or optical differences in the cornea associated with high myopia.