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Updated: Feb 7, 2026

Competitive Homing Assays to Study Gut-tropic T Cell Migration
Published on: March 1, 2011
Acting on non-communicable diseases in low- and middle-income tropical countries
Majid Ezzati1,2,3, Jonathan Pearson-Stuttard4,5, James E Bennett4,5
1Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. majid.ezzati@imperial.ac.uk.
Abstract:
The classical portrayal of poor health in tropical countries is one of infections and parasites, contrasting with wealthy Western countries, where unhealthy diet and behaviours cause non-communicable diseases (NCDs) such as heart disease and cancer. Using international mortality data, we show that most NCDs cause more deaths at every age in low- and middle-income tropical countries than in high-income Western countries. Causes of NCDs in low- and middle-income countries include poor nutrition and living environment, infections, insufficient taxation and regulation of tobacco and alcohol, and under-resourced and inaccessible healthcare. We identify a comprehensive set of actions across health, social, economic and environmental sectors that could confront NCDs in low- and middle-income tropical countries and reduce global health inequalities.
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