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Ocular hypertension in patients with central/hemicentral retinal vein occlusions: cumulative prevalence and

Dan Călugăru1, Mihai Călugăru1, Ştefan Ţălu2

  • 1Department of Ophthalmology, University of Medicine, Cluj-Napoca 400467, Romania.

International Journal of Ophthalmology
|July 27, 2018
PubMed

Insights

Ocular hypertension (OH) is prevalent in central/hemicentral retinal vein occlusion (C/HCRVO) patients. Prompt treatment of OH in C/HCRVO patients effectively prevents conversion to primary open-angle glaucoma (POAG).

Area of Science:

  • Ophthalmology
  • Vascular Medicine

Background:

  • Central/hemicentral retinal vein occlusions (C/HCRVOs) can be associated with ocular hypertension (OH).
  • Understanding the prevalence and management of OH in C/HCRVO patients is crucial for preventing glaucoma progression.

Purpose of the Study:

  • To prospectively evaluate the cumulative prevalence of ocular hypertension (OH) in patients with unilateral acute central/hemicentral retinal vein occlusions (C/HCRVOs).
  • To assess the management and 3-year outcomes of OH in this patient cohort, focusing on conversion to primary open-angle glaucoma (POAG).

Main Methods:

  • A prospective study of 57 patients with unilateral acute C/HCRVOs.
  • Comprehensive ophthalmological examinations were performed.
  • OH was treated with medication aiming for intraocular pressure (IOP) <21 mm Hg and >22% reduction; patients with a >5% risk of POAG conversion were treated.

Main Results:

  • The cumulative prevalence of OH in C/HCRVO patients was 29.4%.
  • The mean 5-year risk score for OH conversion to POAG was 11.7%±5.4%.
  • Treatment significantly reduced IOP from 25.67±2.16 mm Hg to 18.73±2.96 mm Hg, with no conversions to POAG observed.

Conclusions:

  • Increased OH prevalence in C/HCRVO suggests OH is a risk factor for venous occlusion.
  • Patients with OH and C/HCRVO are at high risk for POAG.
  • OH medication effectively prevented POAG conversion over 3 years.
Abstract

Keywords:
acute central/hemicentral retinal vein occlusionintraocular pressureocular hypertensionprimary open-angle glaucomarisk factor

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