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Changes in choroidal thickness in healthy pediatric individuals: a longitudinal study
Eiko Ohsugi1,2, Yoshinori Mitamura2, Kayo Shinomiya2
1Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji 671-1227, Japan.
International Journal of Ophthalmology
|July 27, 2018
Summary
Choroidal thickness significantly decreased in healthy Japanese children over 1.5 years. This thinning correlated with increased axial length, body height, and weight, suggesting these factors influence pediatric eye development.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Optical Coherence Tomography
Background:
- Choroidal thickness is a key indicator of ocular health.
- Longitudinal data on choroidal thickness changes in healthy children is limited.
- Understanding factors influencing choroidal development is crucial for early detection of eye conditions.
Purpose of the Study:
- To longitudinally assess changes in choroidal thickness in healthy pediatric subjects.
- To identify ocular and systemic factors correlated with choroidal thickness variations.
- To provide normative data for pediatric choroidal development.
Main Methods:
- A longitudinal study involving 34 healthy Japanese children (64 eyes).
- Swept-source optical coherence tomography (SS-OCT) used for retinal and choroidal imaging.
- Choroidal thickness mapped across nine sectors; axial length, height, and weight also measured.
Main Results:
- Mean central choroidal thickness significantly decreased from baseline (301.8 µm) to follow-up (286.6 µm) (P<0.001).
- Choroidal thinning was most pronounced in central sectors and correlated negatively with age, body height, body weight, and axial length elongation.
Conclusions:
- Pediatric choroidal thickness significantly decreases during early childhood.
- Axial length elongation is a primary factor associated with this choroidal thinning.
- These findings are important for evaluating retinochoroidal disorders in young children.
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