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Related Concept Videos

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Updated: Feb 7, 2026

Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization IR-MALDESI
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An Orbitrap-based laser desorption/ablation mass spectrometer designed for spaceflight.

Ricardo Arevalo1, Laura Selliez2,3, Christelle Briois2

  • 1Department of Geology, University of Maryland, College Park, MD, 20742, USA.

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A new spaceflight mass analyzer, the CosmOrbitrap, can detect key elements and organic molecules in cryogenic planetary environments. This technology is crucial for searching for extraterrestrial life and understanding organic synthesis on other worlds.

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Area of Science:

  • Planetary Science
  • Astrobiology
  • Analytical Chemistry

Background:

  • Cryogenic planetary environments are prime targets for astrobiological research.
  • Next-generation instruments are needed for precise elemental and molecular analysis in space.
  • Separation of isobaric interferences is critical for accurate stoichiometry determination.

Purpose of the Study:

  • To evaluate a spaceflight-adapted Orbitrap mass analyzer (CosmOrbitrap) for planetary exploration.
  • To assess the instrument's capability for ultrahigh resolution laser desorption/ablation mass spectrometry.
  • To characterize diverse planetary analog samples.

Main Methods:

  • Utilized a spaceflight-adapted Orbitrap analyzer (CosmOrbitrap) with a pulsed UV laser.
  • Analyzed planetary analog samples including jarosite, magnesium sulfate, uracil, and amino acids.
  • Employed ultrahigh resolution laser desorption/ablation mass spectrometry.

Main Results:

  • Achieved ultrahigh mass resolution (m/Δm ≥ 120,000) for major elements and organic molecules.
  • Quantified isotopic abundances with <1.0% precision and identified masses within 3.2 ppm accuracy.
  • Detected twelve amino acids at concentrations as low as 1 pmol/mm².

Conclusions:

  • The CosmOrbitrap offers unparalleled mass resolution and accuracy for spaceflight applications.
  • This instrument is a mission-enabling technology for advancing planetary exploration.
  • The CosmOrbitrap is highly sensitive and capable of detecting complex organic molecules in extraterrestrial environments.