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Updated: Feb 7, 2026

Translational Orthotopic Models of Glioblastoma Multiforme
Published on: February 17, 2023
Advances in Glioblastoma Operative Techniques
Evan D Bander1, Rajiv Magge2, Rohan Ramakrishna1
1Department of Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA.
Achieving complete surgical resection is vital for glioblastoma (GBM) patient survival. New surgical tools and minimally invasive techniques aim to improve tumor removal and patient outcomes.
Area of Science:
- Neurosurgery
- Oncology
- Medical Technology
Background:
- Glioblastoma (GBM) survival is significantly linked to the extent of surgical tumor resection.
- Current surgical limitations necessitate advancements for improved patient outcomes.
- Glioblastoma is a highly aggressive primary brain tumor with poor prognosis.
Purpose of the Study:
- To review recent advancements in surgical techniques and technologies for glioblastoma resection.
- To highlight the role of improved imaging and minimally invasive approaches in neurosurgery for GBM.
- To discuss the impact of these innovations on achieving higher rates of complete tumor resection.
Main Methods:
- Review of current literature on surgical techniques for glioblastoma.
- Analysis of advances in intra-operative imaging, fluorescent agents, and functional imaging.
- Exploration of emerging minimally invasive treatment strategies for GBM.
Main Results:
- Enhanced visualization tools improve the identification of tumor margins and critical brain structures.
- Advanced techniques facilitate safer and more extensive tumor resections.
- Development of novel minimally invasive methods offers alternative treatment options.
Conclusions:
- Surgical resection remains a cornerstone in glioblastoma management.
- Technological innovations are crucial for improving the safety and efficacy of GBM surgery.
- Ongoing research into advanced and minimally invasive techniques holds promise for better patient survival and quality of life.
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