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Updated: Feb 7, 2026
Human Placental and Decidual Organ Cultures to Study Infections at the Maternal-fetal Interface
Published on: July 21, 2016
[Epidemiology of bacterial infection materno-fetal at Abidjan- Ivory Cost: prospective study of eighty (80) cases]
R N'guessan1, V Gbonon2, F Dick-Amon Tanoh1
1Service de Néonatologie CHU de Yopougon 22 BP 1347 Abidjan 22. Côte d'Ivoire.
Abstract:
The aim of our study was to describe the risk factors, clinical symptoms and bacteria isolated during fetal-maternal bacterial infections in hospitals.
Materials And Methods:
This was a prospective, descriptive study conducted from August 2, 2007 to October 3, 2007 at the neonatology department and the delivery room of the Yopougon teaching hospital . All newborn babies presenting a risk factor of infection have been included in this study. A bacteriological evaluation including containing central, peripheral and gastric fluid samples was performed. Bacteriological tests (NFS, CRP, PCT) were also performed on those newborn babies.
Results:
Eighty newborn babies were included. The maternal risk factors were dominated by prolonged breaking of membranes 62.5%. In the newborn bad APGAR score 56.3% and prematurity 18.8%, were noted. The main clinical symptoms were neurological, , respiratory and digestive 52.5%, 44.4% 37.5%, respectively. The main pathogens isolated were 65.5% Staphylococcus coagulase negative, 13.8% Staphylococcus aureus, 6.9% Pseudomonas aeruginosa, 3,4% Klebsiella pneumoniae, and 3.4% Acinetobacter Sp.
Conclusion:
The clinical symptoms of the fetal-maternal bacterial infections are polymorphic. Germs found in our study differ from those usually found in the fetal-maternal bacterial infections in Europe.
Insights
This study identified key risk factors and common bacterial pathogens in hospital-acquired fetal-maternal infections. Findings highlight prevalent symptoms and pathogens, differing from European data, aiding targeted neonatal care.
Area of Science:
- Neonatal infections
- Bacteriology
- Maternal-fetal health
Context:
- Fetal-maternal bacterial infections pose significant risks to newborns.
- Understanding local epidemiology is crucial for effective treatment.
Purpose:
- To describe risk factors, clinical symptoms, and isolated bacteria in hospital-acquired fetal-maternal infections.
- To compare findings with existing literature, particularly European data.
Summary:
- A prospective study at Yopougon teaching hospital included 80 newborns with infection risk factors.
- Prolonged membrane rupture was a major maternal risk factor. Neonatal symptoms included neurological, respiratory, and digestive issues.
- Commonly isolated bacteria were *Staphylococcus coagulase negative*, *Staphylococcus aureus*, *Pseudomonas aeruginosa*, *Klebsiella pneumoniae*, and *Acinetobacter Sp*.
Impact:
- Provides essential epidemiological data on fetal-maternal infections in a specific region.
- Highlights differences in prevalent pathogens compared to European settings.
- Informs clinical practice and infection control strategies for neonatal units.
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