Related Experiment Video
Updated: Feb 7, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
Intraoperative lagophthalmos formula for levator resection in congenital ptosis
Sunah Kang1, Ji Won Seo2, Chan Joo Ahn1
1Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Insights
A new formula helps predict intraoperative lagophthalmos in congenital ptosis surgery. This aids surgeons in determining levator resection amounts for better outcomes.
Area of Science:
- Ophthalmology
- Surgical Research
- Pediatric Surgery
Background:
- Congenital ptosis is a common condition requiring surgical correction.
- Levator resection is a primary surgical technique for ptosis.
- Predicting intraoperative variables is crucial for optimizing surgical outcomes.
Purpose of the Study:
- To develop a regression formula for intraoperative lagophthalmos.
- To guide the amount of correction in levator resection for congenital ptosis.
- To improve surgical outcomes in mild to moderate congenital ptosis.
Main Methods:
- Retrospective study of 38 eyelids in 28 children with congenital ptosis.
- Analysis of preoperative margin reflex distance-1 (MRD1) and levator function.
- Stepwise multiple regression analysis to correlate intraoperative lagophthalmos with preoperative factors.
Main Results:
- Mean intraoperative lagophthalmos was 7.4±0.9 mm.
- Significant negative correlation found between intraoperative lagophthalmos and preoperative MRD1 (r=0.55) and levator function (r=0.53).
- Regression formula derived: Intraoperative lagophthalmos = 9.08 - 0.48×Preoperative MRD1 - 0.26×Levator function (r=0.60).
Conclusions:
- Intraoperative lagophthalmos negatively correlates with preoperative MRD1 and levator function.
- The derived formula provides a stronger correlation by incorporating both variables.
- This formula can assist surgeons in calculating surgical correction for improved outcomes in congenital ptosis surgery.
Aim:
To calculate a regression formula for intraoperative lagophthalmos to determine the amount of correction in levator resection for mild to moderate congenital ptosis.
Methods:
This retrospective study included 38 eyelids from 28 consecutive children with congenital ptosis with levator function of 4 mm or better who showed satisfactory surgical outcomes defined as postoperative margin reflex distance-1 (MRD1) ≥3 mm in each eye and difference in MRD1 ≤1 mm between eyes at 6 months after levator resection. We investigated whether the degree of intraoperative lagophthalmos measured by calliper correlated with the preoperative values of MRD1, levator function and age. A stepwise multiple regression analysis was performed with intraoperative lagophthalmos as the dependent variable.
Results:
The mean intraoperative lagophthalmos was 7.4±0.9 mm (range, 6-10 mm). The intraoperative lagophthalmos was found to have a statistically significant negative correlation with preoperative MRD1 (r =0.55, p<0.0001) and levator function (r =0.53, p<0.0001), respectively. A stepwise multiple regression analysis resulted in the following regression formula: Intraoperative lagophthalmos=9.08 - 0.48×Preoperative MRD1 - 0.26×Levator function (r =0.60, p<0.0001).
Conclusion:
Intraoperative lagophthalmos in patients with satisfactory surgical outcome correlated negatively with both preoperative MRD1 and levator function and accounting for both variables resulted in a stronger correlation than either variable alone. Surgeons would be able to calculate the amount of surgical correction using this formula of intraoperative lagophthalmos, which could lead to a satisfactory surgical outcome in levator resection for congenital ptosis.
Related Concept Videos
Chemical Formulas
Ionic Compounds: Formulas and Nomenclature
Molecular Compounds: Formulas and Nomenclature
Experimental Determination of Chemical Formula
Formula Mass and Mole Concepts of Compounds
The Midpoint Formula

