Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

1.8K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achievement and Maintenance of Remission with Upadacitinib in Patients with Moderate-to-Severe Rheumatoid Arthritis in Italy: 1-Year Data from UPHOLD, a Prospective Real-World Observational Study.

Rheumatology and therapy·2026
Same author

Comparative effectiveness and persistence of ixekizumab and other b/tsDMARDs in patients with PsA from a real-world setting: 12-month results from the PRO-SPIRIT study.

RMD open·2026
Same author

Influence of Biological Sex on Participant Characteristics, Guselkumab Efficacy and Radiographic Progression in Active Psoriatic Arthritis: Post Hoc Analysis of Three Randomized Trials.

Rheumatology and therapy·2025
Same author

Detection and Clinical Associations of Autoantibodies to Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A2/B1 in Patients with Systemic Sclerosis.

International journal of molecular sciences·2025
Same author

Interleukin-6 signalling: what rheumatologists should know and expect.

Reumatologia·2025
Same author

Multi-domain effectiveness of guselkumab evaluated via composite indices through 1 year in patients with PsA and inadequate response to TNFi: post hoc analysis of COSMOS.

Rheumatology (Oxford, England)·2024
Same journal

Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes.

Clinical reviews in allergy & immunology·2026
Same journal

β-blocker Therapy in Cholinergic Urticaria, Adrenergic Urticaria and the Aquagenic Continuum Beta-Blocker Therapy in Chronic Inducible Urticaria.

Clinical reviews in allergy & immunology·2026
Same journal

Immunopathogenesis and Cytokine Pathways in Reactive Infectious Mucocutaneous Eruption (RIME) in Pediatric Population: Infectious Triggers and Molecular Insights.

Clinical reviews in allergy & immunology·2026
Same journal

Neuropsychological Factors in Vitiligo: Mechanisms and Clinical Application.

Clinical reviews in allergy & immunology·2026
Same journal

Tertiary Lymphoid Structure: A Potential Therapeutic Target Affecting Immune Response in Autoimmune Diseases.

Clinical reviews in allergy & immunology·2026
Same journal

Differentiating Acute-onset Autoimmune Hepatitis From Drug-Induced Autoimmune-like Hepatitis: A Multicenter Study and Score Development.

Clinical reviews in allergy & immunology·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis
05:44

A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis

Published on: December 9, 2022

4.6K

Autoimmunity in 2017.

Carlo Selmi1,2

  • 1Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, via A. Manzoni 56, 20089 Rozzano, Milan, Italy. carlo.selmi@unimi.it.

Clinical Reviews in Allergy & Immunology
|July 28, 2018
PubMed
Summary
This summary is machine-generated.

Research on autoimmunity surged in 2017, with significant advances in rheumatoid arthritis, lupus, and systemic sclerosis. New insights into pathogenesis and treatments are emerging for these autoimmune diseases.

Keywords:
AutoantibodyImmune checkpoint inhibitorsImmune tolerancePlateletTh17

More Related Videos

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Published on: December 17, 2010

11.9K
The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
09:03

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice

Published on: February 3, 2012

19.9K

Related Experiment Videos

Last Updated: Feb 7, 2026

A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis
05:44

A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis

Published on: December 9, 2022

4.6K
Induction of Experimental Autoimmune Hypophysitis in SJL Mice
10:38

Induction of Experimental Autoimmune Hypophysitis in SJL Mice

Published on: December 17, 2010

11.9K
The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
09:03

The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice

Published on: February 3, 2012

19.9K

Area of Science:

  • Immunology and Autoimmune Diseases

Background:

  • The keyword "autoimmunity" saw a significant increase in peer-reviewed publications in 2017 compared to 2016.
  • Autoimmunity research maintained a stable share within the broader immunology field.

Purpose of the Study:

  • To analyze trends in basic and clinical autoimmune disease research.
  • To highlight key advancements in rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.

Main Methods:

  • Arbitrary analysis of articles in leading immunology and autoimmunity journals.
  • Review of research published during the 2017 solar year.

Main Results:

  • Major research progress was observed in rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.
  • New data on pregnancy in lupus and biomarkers in systemic sclerosis may alter clinical management.
  • Significant findings in rheumatoid arthritis include insights into pathogenesis (e.g., platelets), phenotyping, and treatments.
  • Cancer immunotherapy (immune checkpoint modulation) is paralleled by research into its autoimmune side effects and paraneoplastic syndromes.

Conclusions:

  • 2017 was a pivotal year for autoimmune disease research, with significant findings across multiple conditions.
  • Emerging data suggests a transformative impact on understanding and managing autoimmune diseases.
  • Further extensive studies are anticipated based on the 2017 findings.