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[Correlation between Movement Distance of Small Intestinal Contents and Survival Time in Female Rats after Feeding].

L Chen1, J J Fang1, G Meng2

  • 1Institute of Forensic Science, Department of Anhui Public Security, Hefei 230061, China.

Fa Yi Xue Za Zhi
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Summary

The movement distance of small intestinal contents in female Sprague Dawley (SD) rats correlates with survival time after feeding. This finding aids in estimating the postmortem interval in forensic investigations.

Keywords:
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Area of Science:

  • Forensic Science
  • Animal Models
  • Physiology

Background:

  • Accurate postmortem interval estimation is crucial in forensic science.
  • Gastric and intestinal content analysis offers potential for time-since-death determination.
  • Standardized animal models are needed to validate forensic methods.

Purpose of the Study:

  • To investigate the relationship between small intestinal content movement and survival time in female SD rats.
  • To assess the utility of this relationship for estimating the postmortem interval.
  • To establish a reliable animal model for forensic research.

Main Methods:

  • Female SD rats were divided into control (fasting) and postprandial groups (1-5 hours after feeding).
  • Rats were sacrificed at designated times; stomach and small intestinal contents were analyzed.
  • Movement distance of intestinal contents was measured and statistically analyzed.

Main Results:

  • Control rats had empty stomachs; postprandial rats showed progressive changes in gastric and intestinal contents.
  • The movement distance of intestinal contents increased over time post-feeding.
  • Statistically significant differences (P<0.05) were observed between groups.

Conclusions:

  • A 24-hour fasting followed by 1-hour feeding protocol creates a suitable model in female SD rats.
  • Changes in small intestinal contents provide an experimental basis for postmortem interval estimation in forensic practice.