Related Experiment Video
Updated: Feb 7, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Distribution based Fuzzy Estimate Spectral Clustering for Cancer Detection with Protein Sequence and Structural
Thenmozhi K1, Karthikeyani Visalakshi N, Shanthi S
1Department of Computer Applications, Selvam College of Technology, Namakkal, TamilNadu, India.
Abstract:
Objective: In biological data analysis, protein sequence and structural motifs are an amino-acid sequence patterns that are widespread and used as tools for detecting the cancer at an earlier stage. To improve the cancer detection with minimum space and time complexity, Distribution based Fuzzy Estimate Spectral Clustering (DFESC) technique is developed. Methods: Initially, the protein sequence motifs are taken from dataset to form the cluster. The Distribution based spectral clustering is applied to group the protein sequence by measuring the generalized jaccard similarity between each protein sequences. To develop the clustering accuracy, soft computing technique namely fuzzy logic is applied to calculate membership value of each sequence motifs. Results: The outcome showed that the presented DFESC technique effectively identifies the cancer in terms of clustering accuracy, false positive rate, and cancer detection time and space complexity. Conclusion: Based on the observations, evaluation of DFESC technique provides improved result for premature detection of cancer using protein sequence and structural motifs.
Related Concept Videos
Protein and Protein Structure
A protein's shape is critical to its function. For example, an enzyme...
Distributions to Estimate Population Parameter
Structural Protein Function
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
Structural Protein Function
Protein and Protein Structures
Additional Subnuclear Structures
The nucleus contains many membrane-less subnuclear organelles or nuclear bodies, such as nucleoli, Cajal bodies, speckles,...

