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Updated: Feb 7, 2026
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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD
Published on: October 10, 2012
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Is Suicidal Behavior in Mood Disorders Altered by Comorbid PTSD?
René M Lento1,2,3, Amanda Carson-Wong1,2, Jonathan D Green1,4
11 VA Boston Healthcare System, Boston, MA, USA.
Crisis
|July 28, 2018
Summary
Veterans with comorbid mood disorder and PTSD were more likely to self-injure impulsively and while using substances. Safety planning for impulsive suicide attempts is crucial for these veterans.
Area of Science:
- Psychiatry
- Military Mental Health
- Suicidology
Background:
- Suicide is a significant cause of death among US veterans.
- Existing research links depression and PTSD to suicidal behaviors in veterans.
- Limited research explores variations in self-injurious behavior (SIB) across different diagnostic groups.
Purpose of the Study:
- To identify clinically significant differences in SIB between veterans with comorbid mood disorder and PTSD (CMP) and those with mood disorder alone (MDA).
Main Methods:
- The study included 57 US military veterans who reported intentional SIB.
- The Post Self-Injury/Attempted Self-Injury Debriefing Interview was used to gather data on SIB characteristics.
Main Results:
- Veterans with CMP were more prone to reporting impulsive SIB compared to those with MDA.
- A higher incidence of substance use during self-injury was reported by veterans with CMP.
Conclusions:
- Safety planning interventions, particularly means restriction, may be vital for veterans with CMP to mitigate impulsive suicide attempts.
- Findings suggest tailored clinical approaches are needed for veterans with co-occurring mental health conditions.
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