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Necrotizing Scleritis After Cosmetic Conjunctivectomy With Mitomycin C.
Yong Woo Ji1, Si Yoon Park2, Ji Won Jung3
1Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Department of Ophthalmology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
American Journal of Ophthalmology
|July 28, 2018
Summary
Cosmetic eye whitening surgery using mitomycin C can lead to necrotizing scleritis, a serious complication. Prompt anti-inflammatory treatment and surgical intervention are crucial for managing this condition.
Area of Science:
- Ophthalmology
- Surgical Complications
- Ocular Surface Disease
Background:
- Cosmetic conjunctivectomy, often using mitomycin C (MMC), is performed for eye-whitening purposes.
- Necrotizing scleritis is a potential sight-threatening complication following such procedures.
Observation:
- A retrospective case series identified 4 patients who developed necrotizing scleritis after cosmetic eye-whitening surgery.
- The average time from surgery to diagnosis was 51 months, with all cases being unilateral.
Findings:
- No systemic autoimmune or infectious causes were identified in the affected patients.
- Three patients underwent conjunctival flap surgery, and all received oral corticosteroids for anti-inflammatory treatment.
Implications:
- Necrotizing scleritis following cosmetic eye-whitening with MMC can be extensive and severe.
- Effective management requires prompt anti-inflammatory therapy and surgical intervention.
