5-Hydroxy-γ-decalactone production by Bacillus sp. 1s-1 and its complete genome sequence
Zijun Xiao1, Lingyan Ma1, Jing-Yi Zhao1
1Center for Bioengineering and Biotechnology, State Key Laboratory of Heavy Oil Processing, China University of Petroleum (East China), Qingdao 266580, China.
Abstract:
Lactones are useful flavor compounds and some 5-hydroxy-γ-butyrolactones also have important biological activities. In this study, a newly isolated Bacillus strain 1s-1 was identified to be capable of producing 5-hydroxy-γ-decalactone (HDL) from peanut oil by gas chromatography-mass spectrometry and authentic standards. The complete genome of this strain was sequenced and de novo assembled to a single circular chromosome of 4,166,290 bp with a guanine-cytosine content of 46.3%. The biosynthesis pathway of HDL in strain 1s-1 was postulated and this study provides helpful information for further utilizing Bacillus sp. 1s-1 as a source of valuable hydroxy lactones.
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