Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

56.1K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.1K
Introduction to Special Senses01:26

Introduction to Special Senses

7.6K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.6K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

806
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
806
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

637
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
637
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

742
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
742
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

581
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
581

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single-shot ablation for AF: Real-world procedural and one-year outcomes with the newly adopted PulseSelect PFA compared with cryoballoon from the 1STOP project.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same author

Insulin-treated type 2 diabetes is associated with increased mortality after transvenous lead extraction for device infection: the IN2DEEP study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Sex Differences in Cancer and Cardiotoxicity: Mechanisms, Outcomes, and Clinical Implications Across Solid and Hematological Malignancies.

Cancers·2026
Same author

Artificial Intelligence in Biomedical Scientific Publishing.

European heart journal·2026
Same author

Sedation Strategies, Drugs, and Protocols Used in Catheter Ablation of Atrial Fibrillation: A Focused Review.

Reviews in cardiovascular medicine·2026
Same author

CT-guided lead placement prevents P-wave oversensing in extravascular ICD.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same journal

Comparing Ferric Carboxymaltose Versus Iron Sucrose in Patients with Heart Failure.

Clinical cardiology·2026
Same journal

Beyond Rural Versus Urban: Referral Pathways and Structural Heart Programs May Influence Outcomes After Left Atrial Appendage Occlusion.

Clinical cardiology·2026
Same journal

Strauss-Defined LBBB Identifies Patients With Improved Outcomes After CRT-D: A Comparative Cohort Study.

Clinical cardiology·2026
Same journal

Does Serum γKlotho Truly Provide Incremental Prognostic Value Beyond Established Risk Predictors in Multivessel Coronary Artery Disease?

Clinical cardiology·2026
Same journal

Associations of the C-Reactive Protein-Albumin-Lymphocyte Index, Red Cell Distribution Width-Albumin Ratio, and Blood Urea Nitrogen-Albumin Ratio With All-Cause and Cardiovascular Mortality Among Adults With Preclinical Heart Failure.

Clinical cardiology·2026
Same journal

Real-World National Databases Versus Hypothesis-Driven Cohort Studies: A Reply to the Critique on the TURK-HF Registry Design.

Clinical cardiology·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.7K

Is ventricular sensing always right, when it is left?

Mauro Biffi1, Giulia de Zan1, Giulia Massaro1

  • 1Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.

Clinical Cardiology
|July 29, 2018
PubMed
Summary
This summary is machine-generated.

Left ventricular lead sensing is a viable alternative for cardiac implantable electronic devices when right ventricular sensing is not feasible. This approach offers reliable performance and avoids complications associated with traditional right ventricular lead placement.

Keywords:
Arrhythmia detectionCardiac stimulationLeft ventricular leadSensingTricuspid regurgitation

More Related Videos

Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
07:55

Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice

Published on: April 7, 2022

3.7K
Measuring Left Ventricular Pressure in Late Embryonic and Neonatal Mice
08:15

Measuring Left Ventricular Pressure in Late Embryonic and Neonatal Mice

Published on: February 23, 2012

14.5K

Related Experiment Videos

Last Updated: Feb 7, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.7K
Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
07:55

Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice

Published on: April 7, 2022

3.7K
Measuring Left Ventricular Pressure in Late Embryonic and Neonatal Mice
08:15

Measuring Left Ventricular Pressure in Late Embryonic and Neonatal Mice

Published on: February 23, 2012

14.5K

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Electrophysiology

Background:

  • Conventional ventricular sensing in cardiac implantable electronic devices (CIEDs) relies on the right ventricular (RV) channel.
  • This practice evolved from earlier epicardial sensing methods used in pacemakers and implantable cardioverter-defibrillators (ICDs).

Purpose of the Study:

  • To evaluate the reliability of left ventricular (LV) sensing using transvenous leads positioned in the coronary veins.
  • To assess the feasibility of LV sensing as an alternative to RV sensing in specific clinical scenarios.

Main Methods:

  • LV leads were utilized for sensing and arrhythmia detection in patients where RV lead placement was challenging or suboptimal.
  • Indications included difficult tricuspid valve crossing, unsuitable RV signals for arrhythmia detection, or RV lead sensing failure in cardiac resynchronization therapy defibrillator (CRTD) recipients.

Main Results:

  • Thirty-seven patients received IS-1 LV leads connected to the RV port of CIEDs, including pacemakers, CRTPs, ICDs, and CRTDs.
  • Over a median follow-up of 41 months, lead performance was stable with no instances of undersensing or non-cardiac oversensing.
  • Ventricular tachycardia/fibrillation (VT/VF) were accurately detected and treated; reprogramming was needed in a few CRTD recipients due to transient QRS counting or T-wave oversensing.

Conclusions:

  • Transvenous LV lead sensing is a feasible option for CIEDs.
  • Enhanced sensing programmability is crucial for addressing RV lead issues in cardiac resynchronization therapy (CRT) without infection risk or lead redundancy.
  • This approach is becoming essential due to evolving lead technologies like DF-4 and quadripolar leads, impacting lead interchangeability.