Related Experiment Video

Updated: Feb 7, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

6.6K

Retrospective study recommends endoscopy when diagnosing lymphocytic colitis or eosinophilic gastrointestinal

Jens Tilma1, Jørgen Tilma2, Karen Tilma3

  • 1Sygehus Lillebaelt, Vejle, Denmark.

Acta Paediatrica (Oslo, Norway : 1992)
|July 29, 2018
PubMed

Insights

This study found that lymphocytic colitis (LC) and eosinophilic gastrointestinal disease (EGID) affect 4.2% of children with severe recurrent abdominal pain (RAP). Endoscopy is recommended for diagnosis, as medical treatments and diets effectively manage symptoms.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Pathology
  • Clinical Diagnostics

Background:

  • Recurrent abdominal pain (RAP) is a common pediatric complaint.
  • Diagnosing the underlying cause of severe RAP can be challenging.
  • Lymphocytic colitis (LC) and eosinophilic gastrointestinal diseases (EGID) are increasingly recognized conditions.

Purpose of the Study:

  • To determine the prevalence of LC and EGID in children with severe RAP.
  • To describe the clinical presentation, diagnostic methods, and outcomes for these conditions.
  • To evaluate the effectiveness of treatment strategies.

Main Methods:

  • Retrospective follow-up study at a Danish regional hospital.
  • Reviewed histology reports of children undergoing gastrointestinal endoscopy for RAP (2011-2016).
  • Included 381 patients in the diagnostic process for RAP, with 74 undergoing endoscopy.

Main Results:

  • 16 out of 74 children (21.6%) were diagnosed with LC and/or EGID.
  • This represents 4.2% of the total RAP patient cohort.
  • Severe RAP was the predominant symptom; endoscopy revealed normal mucosa, but specific histopathology confirmed diagnoses. No biochemical abnormalities were noted.

Conclusions:

  • LC and/or EGID are found in a significant subset of children with severe RAP.
  • Endoscopic evaluation is crucial for diagnosing these conditions, especially when routine tests are normal.
  • Medical treatment and dietary modifications are effective in achieving clinical remission.
Abstract

Keywords:
Eosinophilic gastrointestinal diseaseHistopathologyLymphocytic colitisPaediatricRecurrent abdominal pain

More Related Videos

Studying Brain Function in Children Using Magnetoencephalography08:00

Studying Brain Function in Children Using Magnetoencephalography

Published on: April 8, 2019

9.6K
Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study09:36

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study

Published on: June 6, 2025

584

Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.3K
Diagnosing Acidosis and Alkalosis01:24

Diagnosing Acidosis and Alkalosis

Diagnosing acid-base imbalances involves systematically analyzing arterial blood samples, focusing on three key measurements: pH, bicarbonate (HCO3−) concentration, and carbon dioxide partial pressure (PCO2). This analysis follows a four-step process that helps identify the imbalance's underlying cause and nature.
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2  and...
1.3K
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
428
Anatomy of the Gastrointestinal System01:26

Anatomy of the Gastrointestinal System

The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
2.9K
Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
2.4K
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
1.4K