Related Experiment Video

Updated: Feb 7, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

26.3K

Applicability of Carotid Artery Stenting for Patients 80 Years or Older: A Single-Center Experience

Masaru Abiko1, Shigeyuki Sakamoto1, Junichiro Ochiai2

  • 1Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

World Neurosurgery
|July 29, 2018
PubMed

Insights

Carotid artery stenting (CAS) is safe for octogenarians, with no major adverse events in this study. This dual-protection method effectively manages vulnerable plaque and debris in elderly patients undergoing CAS.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Geriatric Medicine

Background:

  • Elderly patients undergoing carotid artery stenosis procedures face higher perioperative stroke risks with stenting compared to endarterectomy.
  • Retrospective analysis of carotid artery stenting (CAS) in patients aged 80 and older was conducted at a single center.

Purpose of the Study:

  • To evaluate the characteristics and perioperative outcomes of CAS in octogenarian patients.
  • To assess the safety and efficacy of a dual-protection and blood-aspiration method for CAS in this age group.

Main Methods:

  • 97 patients with internal carotid artery stenosis underwent CAS using simultaneous flow reversal and distal filter with blood aspiration.
  • Patients were divided into octogenarian (≥80 years) and non-octogenarian groups.
  • Outcomes included patient background, visible debris, in-stent protrusion, major adverse events (stroke, death), and diffusion-weighted imaging findings.

Main Results:

  • CAS procedure success rate was 100% with zero major adverse events within 30 days.
  • Vulnerable plaque was more frequent in octogenarians (50%) than non-octogenarians (26.9%, P=0.047).
  • Visible debris was significantly higher in octogenarians (43.3%) compared to non-octogenarians (22.4%, P=0.004).

Conclusions:

  • Carotid artery stenosis in octogenarians often involves vulnerable plaque.
  • The dual-protection and blood aspiration method enabled safe CAS performance in octogenarian patients.
  • This technique effectively mitigated risks associated with CAS in the elderly population.
Abstract

Keywords:
Carotid artery stentingDual protectionOctogenarian

More Related Videos

Isolation of Endothelial Cells from the Lumen of Mouse Carotid Arteries for Single-Cell Multi-Omics Experiments09:12

Isolation of Endothelial Cells from the Lumen of Mouse Carotid Arteries for Single-Cell Multi-Omics Experiments

Published on: October 4, 2021

3.8K
Author Spotlight: Vascular Tissue Dissociation and Exploring Single-Cell Subclusters for Targeted Therapy04:21

Author Spotlight: Vascular Tissue Dissociation and Exploring Single-Cell Subclusters for Targeted Therapy

Published on: January 19, 2024

3.6K

Related Concept Videos

Patient-centered Care01:13

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
3.1K
Applications of Integration to Find Centers of Mass01:30

Applications of Integration to Find Centers of Mass

Rotational equilibrium provides a natural framework for defining the center of mass of a system. For a plank balanced on a pivot with two unequal masses, equilibrium is achieved when the net torque about the pivot is zero. Torque is defined as the product of a force and its perpendicular distance from the pivot. When the torques due to all forces cancel, the pivot coincides with the center of mass of the system.For a system composed of several discrete point masses, the center of mass lies at...
83
Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
11.7K
Center of Gravity00:58

Center of Gravity

The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.7K
Center of Gravity01:15

Center of Gravity

The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Center of Mass00:59

Center of Mass

The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
2.0K