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Updated: Feb 7, 2026

Observation and Analysis of Blinking Surface-enhanced Raman Scattering
Published on: January 11, 2018
Preparation and characterization of melamine-formaldehyde/Ag composite microspheres with surface-enhanced Raman
Peihua Wen1, Yadong Wang2, Ni Wang1
1Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education, Shaanxi Key Laboratory for Advanced Energy Devices, Shaanxi Engineering Lab for Advanced Energy Technology, School of Materials Science and Engineering, Shaanxi Normal University, Xi'an 710119, China.
Abstract:
A facile and environmentally friendly approach was proposed to decorate Ag nanoparticles on melamine-formaldehyde (MF) colloidal particles (MF/Ag composite microspheres). In this approach, monodisperse MF colloidal particles were prepared via a two-step organic sol-gel process and served as the active templates for the decoration of Ag nanoparticles. Then, the [Ag(NH3)2]+ ions as the Ag precursors can be adsorbed onto the surfaces of the MF colloidal particles and were in situ reduced into metallic Ag nanoparticles, forming MF/Ag composite microspheres. During this synthesis, neither presurface activation nor extra reductants were necessary. These MF/Ag composite microspheres can be used as the surface-enhanced Raman scattering (SERS) active substrates for the trace detection of organic compounds, e.g., 4-aminobenzenethiol (4-ABT) and penicillin G sodium. Furthermore, these MF/Ag composite microspheres also showed excellent antibacterial activities against both Escherichia coli (E. coli, gram-negative bacteria) and Staphylococcus aureus (S. aureus, gram-positive bacteria).
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